High Shear Mixer

LHS Series High Shear Mixer:
High Shear Mixer

The machine is widely used in such industries as drug, food, dairy products, chemical industry, etc. It is a process machine widely applied during production, for example, the production of tablets, capsules, granules, and other wet granules. It has many functions such as mixing, granulating, etc.
The materials are fed into the granulating pot through the vacuum feeder or lifting feeder. After the action of centrifugal force of mixing paddle, the pressure liquid supply system injects the adhesive through the spray gun. Meanwhile, the cutter rotates at a high speed. The materials are bonded into hollow granules in the pot and discharged to the next procedure (granule sizing or drying) after the granulating is finished.
*The main machine adopts the most advanced design concept of SAR LABORTECNIC Company. The pot is of a conical structure.
*As the pot diameter is large, the granules formed are more even. Material reproducibility is ensured reliably.
*The interval between the pot and mixing paddle is controlled to be within 1.5mm. There are no material residues at the bottom of the pot.
*The machine is provided with the terminal control system to provide reliable guarantee for granulating reproducibility.
*It combines gas seal and mechanical seal. It is also provided with gas seal pressure upper and lower limits inspection.
*The machine can be equipped with advanced WIP cleaning system.
*It meets FDA/cGMP requirements for production.
High Shear Mixer

LHSG Series High Shear Mixer:
High Shear Mixer

The machine is widely used in such industries as drug, food, dairy products, chemical industry, etc. It is a process machine widely applied during production, for example, the production of tablets, capsules, granules, and other wet granules. It has many functions such as mixing, granulating, etc.

Working principle

The materials are fed into the granulating pot through the vacuum feeder or lifting feeder. After the action of centrifugal force of mixing paddle, the pressure liquid supply system injects the adhesive through the spray gun. Meanwhile, the cutter rotates at a high speed. The materials are bonded into hollow granules in the pot and discharged to the next procedure (granule sizing or drying) after the granulating is finished.

Structure features:
*The main machine adopts the most advanced design concept of SAR LABORTECNIC Company. The pot is of a conical structure.
*As the pot diameter is large, the granules formed are more even. Material reproducibility is ensured reliably.
*The interval between the pot and mixing paddle is controlled to be within 1.5mm. There are no material residues at the bottom of the pot.
*The machine is provided with the terminal control system to provide reliable guarantee for granulating reproducibility.
*It combines gas seal and mechanical seal. It is also provided with gas seal pressure upper and lower limits inspection.
*The machine can be equipped with advanced WIP cleaning system.
*It meets FDA/cGMP requirements for production.
High Shear Mixer
                             

VALIDATION DOCUMENTATION

TerminologyDefined Meaning
Validation Plan (VP)
 
This document supports the VMP, but provides the detailed validation requirements for a specific piece of equipment.
User Requirement Specification (URS)
 
This document describes what the equipment is intended to do and all essential requirements such as production rates, operating ranges, etc.  The owner usually develops this document.  This document links to the PQ document which tests for each of the requirements.
 
Functional Requirement Specifications (FRS)
 
This document describes the detailed functionality of the equipment.  The supplier usually develops this document.  This document is linked to the OQ document which tests for each function.
 
Design Specifications
(DS)
These documents describe the equipment in sufficient detail to enable it to be built. These documents are linked to the IQ document that tests for all design requirements.
 
Design Qualification (DQ) or Design Reviews
 
Planned and systematic review of specifications, design, and development throughout the life cycle.  Design reviews evaluate deliverables against standards and requirements, identity problems, and propose required corrective actions.
 
Installation Qualification (IQ)
 
Documented verification that all key aspects of the hardware and software installation adhere to appropriate codes and approved design intentions and that the recommendations of the manufacturer have been suitably considered.
 
Operational Qualification (OQ)
 
Documented verification that the equipment-related system or subsystem performs as specified throughout representative or anticipated operating ranges.
 
Factory acceptance test (FAT) Documented verification that the equipment-related system or subsystem performs as specified throughout representative or anticipated operating ranges at manufacturer factory before shipment to end user's workshop.
 
Site acceptance test
(SAT)
Documented verification that the equipment-related system or subsystem performs as specified throughout representative or anticipated operating ranges at site in end user's workshop.
 
Performance Qualification (PQ)
 
Documented verification that the process and / or the total process-related system performs as intended throughout all anticipated operating ranges while operating in its specified operating environment.
 
Commissioning
 
A well planned, documented, and managed engineering approach to the start-up and turnover of facilities, systems, and equipment to the End User that results in a safe and functional environment that meets established design requirements and expectations.
 

V SHAPE MODEL VALIDATION
High Shear Mixer

High Shear Mixer

Equipment Lab

High Shear Mixer
High Shear Mixer

High Shear Mixer
High Shear Mixer
High Shear Mixer

High Shear Mixer